Efficacy of Endolysin LysAB1245 Combined with Colistin as Adjunctive Therapy Against Colistin-Resistant Gram-Negative Bacteria

<b>Background:</b> Colistin resistance among Gram-negative nosocomial pathogens is an increasing concern. The bacteriophage-encoded lytic enzyme endolysin LysAB1245, which targets bacterial peptidoglycan, was evaluated as a potential antibacterial agent in combination with colistin as a...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Rosesathorn Soontarach, Supayang Piyawan Voravuthikunchai, Potjanee Srimanote, Sarunyou Chusri
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Subjects:	antibiotic-resistant bacteria endolysin colistin combination antibacterial agent
Online Access:	https://www.mdpi.com/2079-6382/14/6/538