Computational analysis reveals non-consensus N-glycosylation sequons in antibody Fab region

Protein glycosylation at asparagine typically occurs at a consensus motif. However, recent studies have reported instances of N-glycosylation at non-consensus sites, though the mechanisms and implications of these atypical modifications remain unclear. In this study, we identified novel non-consensu...

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Bibliographic Details

Published in:	mAbs
Main Authors:	Baiyu Qiu, Edwin Chen, Tawnya Flick, Simon Letarte
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Antibody structure fab glycosylation glycan analysis intravenous immunoglobulin mass spectrometry non-consensus N-glycosylation
Online Access:	https://www.tandfonline.com/doi/10.1080/19420862.2025.2574406