Novel Artificial 5′UTR Increase Modified mRNA Translation When Injected into Mouse Heart

<b>Background/Objectives:</b> Modified messenger RNA (modRNA) is a promising gene delivery method used to upregulate genes in cardiac tissue, with applications in both clinical and preclinical settings to prevent cardiac remodeling after ischemic injury. The 5′ untranslated region (5′UTR...

書誌詳細
出版年:	Pharmaceutics
主要な著者:	Ann Anu Kurian, Matteo Ghiringhelli, Eyal Shalom, Gayatri Mainkar, Magdalena M. Żak, Matthew Adjmi, Jeffrey Downey, Seonghun Yoon, Nicole Dubois, Filip K. Swirski, Lior Zangi
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2025-04-01
主題:	modified RNA (modRNA) 5′ untranslated region cardiac gene therapy translation efficiency synthetic RNA motif
オンライン･アクセス:	https://www.mdpi.com/1999-4923/17/4/490

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