The role of bile acid metabolism-related genes in prognosis assessment of hepatocellular carcinoma and identification of NPC1 as a biomarker

Hepatocellular carcinoma (HCC) is one of the most prevalent and deadly cancers worldwide, with a high recurrence rate and poor prognosis. Understanding the molecular mechanisms driving HCC progression is crucial for improving prognostic accuracy and developing targeted therapies. Bile acids (BAs), a...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Maosen Xu, Yu Zhang, Yan Tie, Yiqiao Luo, Yang Wang, Ziqi Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	hepatocellular carcinoma bile acids metabolism NPC1 tumor microenvironment immune
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1588529/full