Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson's disease.

Translation of disease-modifying therapies in neurodegenerative disease has been disappointing. Parkinson's disease (PD) was used to compare patterns of preclinical study design for symptomatic and potentially disease-modifying interventions. We examined the relationship of model, intervention...

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發表在:PLoS ONE
Main Authors: Caroline J Zeiss, Heather G Allore, Amanda P Beck
格式: Article
語言:英语
出版: Public Library of Science (PLoS) 2017-01-01
在線閱讀:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171790&type=printable