Intracellular magnetic hyperthermia reverses sorafenib resistance in hepatocellular carcinoma through its action on signaling pathways

Summary: Sorafenib, a first-line drug for advanced hepatocellular carcinoma (HCC), unfortunately encounters resistance in most patients, leading to disease progression. Traditional approaches to counteract this resistance, particularly those targeting the RAF-MEK-ERK pathway, often face clinical fea...

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Bibliographic Details

Published in:	iScience
Main Authors:	Hugang Li, Zirui Ye, Xun Wang, Jianlan Yuan, Jingyi Guo, Chen Liu, Bin Yan, Haiming Fan, Yi Lyu, Xiaoli Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	Biomedical Engineering Nanomedicine Molecular biology Biomaterials
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224012549