Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity

Estimating the dissolution behavior of a solid in the nasal mucus is challenging for solid dosage forms designed for the nasal application as the solid dissolves into nasal mucus and permeates through the mucosa. In the current study, the dissolution behavior of powders in the artificial nasal fluid...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Daisuke Inoue, Ayari Yamashita, Hideto To
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	nasal formulation powder formulation nasal absorption nasal mucus Calu-3 cell line mucosal permeation
Online Access:	https://www.mdpi.com/1999-4923/14/11/2350