Immuno-Oncology: Emerging Targets and Combination Therapies

Host immunity recognizes and eliminates most early tumor cells, yet immunological checkpoints, exemplified by CTLA-4, PD-1, and PD-L1, pose a significant obstacle to effective antitumor immune responses. T-lymphocyte co-inhibitory pathways influence intensity, inflammation and duration of antitumor...

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发表在:	Frontiers in Oncology
Main Authors:	Henry T. Marshall, Mustafa B. A. Djamgoz
格式:	文件
语言:	英语
出版:	Frontiers Media S.A. 2018-08-01
主题:	combination immunotherapy tumor microenvironment checkpoint blockade personalized therapy biomarkers
在线阅读:	https://www.frontiersin.org/article/10.3389/fonc.2018.00315/full