Inhibition of GPR68 kills glioblastoma in zebrafish xenograft models

Abstract Objective Inhibition and knockdown of GPR68 negatively affects glioblastoma cell survival in vitro by inducing ferroptosis. Herein, we aimed to demonstrate that inhibition of GPR68 reduces the survival of glioblastoma cells in vivo using two orthotopic larval xenograft models in Danio rerio...

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Bibliographic Details
Published in:BMC Research Notes
Main Authors: Leif R. Neitzel, Daniela T. Fuller, Charles H. Williams, Charles C. Hong
Format: Article
Language:English
Published: BMC 2024-08-01
Subjects:
Online Access:https://doi.org/10.1186/s13104-024-06900-x