Sites of gastrointestinal lesion induced by mycophenolate mofetil: a comparison with enteric-coated mycophenolate sodium in rats

Abstract Background Immunosuppressant drugs for renal transplant mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS) cause gastrointestinal (GI) disorders. The specific site of GI tract targeted by MMF and EC-MPS remains unclear. Methods In this study, we investigated the ef...

Full description

Bibliographic Details

Published in:	BMC Pharmacology and Toxicology
Main Authors:	Yichen Jia, Rulin Wang, Long Li, Ying Zhang, Jiawei Li, Jina Wang, Xuanchuan Wang, Guisheng Qi, Ruiming Rong, Ming Xu, Tongyu Zhu
Format:	Article
Language:	English
Published:	BMC 2018-07-01
Subjects:	Enteric-coated mycophenolate sodium Mycophenolate mofetil GI side effects Pharmacokinetics
Online Access:	http://link.springer.com/article/10.1186/s40360-018-0234-1