Imaging mitochondria through bone in live mice using two-photon fluorescence microscopy with adaptive optics

IntroductionMitochondria are extremely important organelles in the regulation of bone marrow and brain activity. However, live imaging of these subcellular features with high resolution in scattering tissues like brain or bone has proven challenging.MethodsIn this study, we developed a two-photon fl...

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Bibliographic Details

Published in:	Frontiers in Neuroimaging
Main Authors:	Tianyi Zheng, Adrian R. Liversage, Kayvan F. Tehrani, Jarrod A. Call, Peter A. Kner, Luke J. Mortensen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Subjects:	two-photon fluorescence microscopy aberration adaptive optics mitochondria mouse cranial bone
Online Access:	https://www.frontiersin.org/articles/10.3389/fnimg.2023.959601/full