External pressure dynamics promote kidney viability and perfusate filtration during ex vivo kidney perfusion

Abstract Normothermic machine perfusion (NMP) has not yet been established as a technique for preserving organs for a day. A key contributing factor to the same is that the perfusing solutions cannot circulate continuously and evenly in the organs. Here, we conceived a method of applying intermitten...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Yuhei Higashi, Jun Homma, Hidekazu Sekine, Hiroki Yago, Eiji Kobayashi, Tatsuya Shimizu
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Online Access:https://doi.org/10.1038/s41598-022-26147-5