Efficacy and mechanism of energy metabolism dual-regulated nanoparticles (atovaquone-albendazole nanoparticles) against cystic echinococcosis

Abstract Background Albendazole (ABZ) and atovaquone (ATO) achieve killing efficacy on Echinococcus granulosus (Egs) by inhibiting energy metabolism, but their utilization rate is low. This study aims to analyze the killing efficacy of ABZ-ATO loading nanoparticles (ABZ-ATO NPs) on Egs. Methods Phys...

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Bibliographic Details

Published in:	BMC Infectious Diseases
Main Authors:	Yuehong Gong, Tianjiao Zhou, Ruijia Ma, Jianhua Yang, Yicong Zhao, Meichi Pan, Zhangjian Huang, Hao Wen, Hulin Jiang, Jianhua Wang
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Atovaquone-albendazole Echinococcus Granulosus Protoscolex Nanoparticles Cystic echinococcosis
Online Access:	https://doi.org/10.1186/s12879-024-09662-w