Duffy Antigen Receptor for Chemokines (DARC) and its Involvement in Patterning and Control of Inflammatory Chemokines

Leukocyte functions are linked to their migratory responses, which, in turn, are largely determined by the expression profile of classical chemokine receptors. Upon binding their cognate chemokines, these G-protein-coupled receptors (GPCRs) initiate signaling cascades and downstream molecular and ce...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Igor eNovitzky-Basso, Antal eRot
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-08-01
Subjects:	Chemokines Endothelial Cells Erythrocytes Inflammation Transcytosis atypical chemokine receptors
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00266/full