Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors

Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or aversively perceived through distinct pathways. Cl− is thought to participate in taste sensation through an unknown mechanism. Here, we describe Cl− ion binding and the response of taste receptor type 1 (T1r),...

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Bibliographic Details

Published in:	eLife
Main Authors:	Nanako Atsumi, Keiko Yasumatsu, Yuriko Takashina, Chiaki Ito, Norihisa Yasui, Robert F Margolskee, Atsuko Yamashita
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2023-02-01
Subjects:	taste receptor salt taste chloride O. latipes
Online Access:	https://elifesciences.org/articles/84291