Celastrol attenuates amphiregulin expression by inhibiting MAPK signaling pathway in triple-negative breast cancer cells

Background: Amphiregulin (AREG) plays an essential role in the metastasis and angiogenesis of various cancers. Purpose: The objective of this study was to investigate the pharmacological effects of celastrol on AREG expression in triple-negative breast cancer (TNBC) cells. Methods: We analyzed the p...

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Bibliographic Details

Published in:	Phytomedicine Plus
Main Authors:	Sangmin Kim, Daeun You, Yisun Jeong, Sun Young Yoon, Eunji Lo, Jeong Eon Lee
Format:	Article
Language:	English
Published:	Elsevier 2022-08-01
Subjects:	Celastrol AREG EGFR MEK/ERK signaling pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667031322001002