A transient mutational burst occurs during yeast colony development

Abstract Characterizing the contribution of mutators to mutation accumulation is essential for understanding cellular adaptation and diseases like cancer. By measuring single and double mutation rates, including point mutations, segmental duplications, and reciprocal translocations, we found that wi...

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Bibliographic Details
Published in:Molecular Systems Biology
Main Authors: Nicolas Agier, Nina Vittorelli, Louis Ollivier, Frédéric Chaux, Alexandre Gillet-Markowska, Samuel O’Donnell, Fanny Pouyet, Gilles Fischer, Stéphane Delmas
Format: Article
Language:English
Published: Springer Nature 2025-06-01
Subjects:
Mutation Rates
Transient Mutator
Yeast
Saccharomyces cerevisiae
Genome Instability
Online Access:https://doi.org/10.1038/s44320-025-00117-1

Internet

https://doi.org/10.1038/s44320-025-00117-1

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