Prospective association between biological aging and risk of hospital-diagnosed MASLD: evidence from the UK Biobank

Background and aimsMetabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disorder linked to increased all-cause and cardiovascular mortality. While accelerated biological aging is a known risk factor for age-related diseases, its role in MASLD remains unclear. Thi...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Xue Yang, Sicheng Li, Qingping Xue, Peijing Yan, Qian Li, Yi Gong, Xiayue Fan, Wenzhi Zhu, Shiyi Wu, Shanshan Zhang, Ko Willems van Dijk, Patrick C.N. Rensen, Ruifang Li-Gao, Yanan Wang, Ting Yao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2026-06-01
Subjects:	age acceleration biological aging lifestyle MASLD mediation
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1853319/full