Thymus research in relation to myasthenia gravis: a new perspective on cell subpopulations and future directions

The thymus generates T cells from immature thymocytes and prevents autoimmune diseases through negative selection and the generation of FOXP3+ regulatory T cells (Tregs). The thymic architecture is typically divided into two distinct microenvironments, the cortex and the medulla. These microenvironm...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Naoko Matsui, Izumi Ohigashi, Alexander Marx
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	myasthenia gravis thymectomy thymic epithelial cell thymic follicular hyperplasia thymoma
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1649171/full