The Role of Extracellular Matrix Remodeling in Skin Tumor Progression and Therapeutic Resistance

The extracellular matrix remodeling in the skin results from a delicate balance of synthesis and degradation of matrix components, ensuring tissue homeostasis. These processes are altered during tumor invasion and growth, generating a microenvironment that supports growth, invasion, and metastasis....

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Bibliographic Details
Published in:Frontiers in Molecular Biosciences
Main Authors: Julia E. Fromme, Paola Zigrino
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.864302/full