Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2

Cadmium (Cd), a notorious environmental pollutant, has been linked to neurological disorders, but the underlying mechanism remains elusive. We aimed to explore the role of microglia in Cd-induced synaptic damages at environmentally relevant doses and whether microglia directly engulf synaptic struct...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Siyao Li, Mingdan You, Chengjie Chen, Jingqi Fu, Yuanyuan Xu, Jingbo Pi, Yi Wang
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Cadmium Microglia Direct engulfment Nrf2 Synapses
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324016968