Body Temperature Drop as a Humane Endpoint in Snake Venom-Lethality Neutralization Tests

Snake venom neutralization potency tests are required for quality control assessment by manufacturers and regulatory authorities. These assays require the use of large numbers of mice that manifest severe signs associated with pain and distress and long periods of suffering. Despite this, many anima...

Full description

Bibliographic Details
Published in:Toxins
Main Authors: Rosa De Jesus, Adam E. Tratner, Alanna Madrid, Andrés Rivera-Mondragón, Goy E. Navas, Ricardo Lleonart, Gabrielle B. Britton, Patricia L. Fernández
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Subjects:
Online Access:https://www.mdpi.com/2072-6651/15/9/525