Pumilio2-deficient mice show a predisposition for epilepsy

Epilepsy is a neurological disease that is caused by abnormal hypersynchronous activities of neuronal ensembles leading to recurrent and spontaneous seizures in human patients. Enhanced neuronal excitability and a high level of synchrony between neurons seem to trigger these spontaneous seizures. Th...

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Bibliographic Details

Published in:	Disease Models & Mechanisms
Main Authors:	Philipp Follwaczny, Rico Schieweck, Therese Riedemann, Antonia Demleitner, Tobias Straub, Anna H. Klemm, Martin Bilban, Bernd Sutor, Bastian Popper, Michael A. Kiebler
Format:	Article
Language:	English
Published:	The Company of Biologists 2017-11-01
Subjects:	RNA-binding protein Pumilio2 PUM2 Epilepsy Epileptogenesis Risk factor
Online Access:	http://dmm.biologists.org/content/10/11/1333