Detection of MCM5 as a novel non-invasive aid for the diagnosis of endometrial and ovarian tumours

Abstract Background MCM5 is a protein involved in DNA replication, facilitating cell proliferation. In normal epithelium MCM5 expression is restricted to the cells in the basal proliferative compartments, however in the presence of a tumour MCM5 positive cells are present at the surface epithelium a...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	J. Stockley, R. Akhand, A. Kennedy, C. Nyberg, E. J. Crosbie, R. J. Edmondson
Format:	Article
Language:	English
Published:	BMC 2020-10-01
Subjects:	Endometrial cancer Ovarian cancer Early detection MCM5 Biomarker
Online Access:	http://link.springer.com/article/10.1186/s12885-020-07468-y