Polyhexamethylene guanidine accelerates the macrophage foamy formation mediated pulmonary fibrosis

Polyhexamethylene guanidine (PHMG) is manufactured and applied extensively due to its superior disinfectant capabilities. However, the inhalatory exposure to PHMG aerosols is increasingly recognized as a potential instigator of pulmonary fibrosis, prompting an urgent call for elucidation of the unde...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	He Sun, Zhijiao Yan, Jiaxing Sun, Jianzhong Zhang, Hongmei Wang, Xinmin Jiang, Mingyue Wang, Xinglin Zhang, Yuting Xiao, Xiaoya Ji, Jinglong Tang, Dunqiang Ren
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	Polyhexamethylene guanidine disinfectant Alveolar macrophages Foam cells Pulmonary fibrosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324001593