Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins

Autophagy is a conserved cellular process involved in the elimination of proteins and organelles. It is also used to combat infection with pathogenic microbes. The intracellular pathogen Legionella pneumophila manipulates autophagy by delivering the effector protein RavZ to deconjugate Atg8/LC3 prot...

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Bibliographic Details

Published in:	eLife
Main Authors:	Aimin Yang, Supansa Pantoom, Yao-Wen Wu
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2017-04-01
Subjects:	Legionella pneumophila autophagy host-pathogen interaction native chemical ligation Sec14 GDI
Online Access:	https://elifesciences.org/articles/23905