Network-based prediction of polygenic disease genes involved in cell motility

Abstract Background Schizophrenia and autism are examples of polygenic diseases caused by a multitude of genetic variants, many of which are still poorly understood. Recently, both diseases have been associated with disrupted neuron motility and migration patterns, suggesting that aberrant cell moti...

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Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Miriam Bern, Alexander King, Derek A. Applewhite, Anna Ritz
Format:	Article
Language:	English
Published:	BMC 2019-06-01
Subjects:	Semi-supervised learning Functional interaction network Schizophrenia Autism Cell motility
Online Access:	http://link.springer.com/article/10.1186/s12859-019-2834-1