Exploring the mechanism of cordycepin combined with doxorubicin in treating glioblastoma based on network pharmacology and biological verification

Background Glioblastoma is the most common and fatal primary malignant tumor in the central nervous system, and the prognosis is poor. Currently, there are no effective treatments for glioblastoma. Cordycepin is a natural active substance with significant anticancer activity and doxorubicin is a bro...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Jing Chen, Yuan-Dong Zhuang, Qiang Zhang, Shuang Liu, Bing-Bo Zhuang, Chun-Hua Wang, Ri-Sheng Liang
Format:	Article
Language:	English
Published:	PeerJ Inc. 2022-02-01
Subjects:	Cordycepin Doxorubicin EMT Network pharmacology Drug combination Glioblastoma
Online Access:	https://peerj.com/articles/12942.pdf