Staphylococcus aureus induces tolerance in human monocytes accompanied with expression changes of cell surface markers

Exposure of human monocytes to lipopolysaccharide (LPS) or other pathogen-associated molecular pattern (PAMPs) induces a temporary insensitivity to subsequent LPS challenges, a cellular state called endotoxin tolerance (ET), associated with the pathogenesis of sepsis. In this study, we aimed to char...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Mario M. Müller, Christian Baldauf, Stella Hornischer, Tilman E. Klassert, Antony Schneegans, Andrea Behnert, Mathias W. Pletz, Stefan Hagel, Hortense Slevogt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	proteomics glycoproteins S. aureus tolerance monocyte membrane proteins
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1046374/full