Postnatal environment affects auditory development and sensorimotor gating in a rat model for autism spectrum disorder

The homozygous Cntnap2 knockout (KO) rat is a well-established genetic model for neurodevelopmental disorders, exhibiting core features of autism spectrum disorder (ASD), including impaired sensory processing and sensorimotor gating. Recent findings indicate that the severity of ASD-like phenotypes...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Ella Elizabeth Doornaert, Alaa El-Cheikh Mohamad, Gurwinder Johal, Brian Leonard Allman, Dorit Möhrle, Susanne Schmid
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	CNTNAP2 auditory processing startle prepulse inhibition gap detection rat
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1565919/full