Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements

Translocation of the LYL1 oncogene are rare in T-cell acute lymphoblastic leukemia, whereas the homologous TAL1 gene is rearranged in approximately 20% of patients. Previous gene-expression studies have identified an immature T-cell acute lymphoblastic leukemia subgroup with high LYL1 expression in...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Irene Homminga, Maartje J. Vuerhard, Anton W. Langerak, Jessica Buijs-Gladdines, Rob Pieters, Jules P.P. Meijerink
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2012-02-01
Online Access:	https://haematologica.org/article/view/6216