Melatonin promoted the therapeutic potential of cisplatin in a rat model of hepatocellular carcinoma: COX-2 and MDM2/p53/miR-155 modulation associated with cytoprotection and tumour regression
Abstract Globally, hepatocellular carcinoma (HCC) presents a clinical and financial burden, as it is often diagnosed at a later stage. Cisplatin is one of the most commonly used chemotherapeutics for treating various types of solid tumours; however, it is a double-edged sword due to its cytotoxic ef...
| الحاوية / القاعدة: | Future Journal of Pharmaceutical Sciences |
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| المؤلفون الرئيسيون: | , , , , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
SpringerOpen
2025-07-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s43094-025-00846-y |