Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

Rheumatoid arthritis (RA), a chronic autoimmune disorder, imposes a substantial global health burden through elevated disability rates, systemic complications, and socioeconomic consequences. Chronic synovitis and progressive joint destruction characterize this disease, driven by dysregulated innate...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Kexin Wang, Haoge Luo, Liping Liu, Hang Gao, Yanyan Song, Dong Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	rheumatoid arthritis (RA) IL-1 autoimmune diseases cytokines immunotherapy monoclonal antibody
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1577628/full