A perspective on challenges and opportunities in characterizing oral cancer stem cells

Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a minority population of cells in a tumor that can self-renew and re-create the heterogeneity of the entire tumor. Cell lines, patient-derived tumor cells, and patient-derived xenografts have all been used to isolate presumptive CSC...

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Bibliographic Details
Published in:Frontiers in Bioscience-Landmark
Main Authors: Subhashini Sadasivam, Ramaswamy Subramanian
Format: Article
Language:English
Published: IMR Press 2020-03-01
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/6/10.2741/4845