Glioma-Associated Sialoglycans Drive the Immune Suppressive Phenotype and Function of Myeloid Cells

The tumor microenvironment of glioblastoma IDH-wildtype is highly immune suppressive and is characterized by a strong component of myeloid-derived suppressor cells (MDSCs). To interfere with the immune suppressive functions of MDSCs, a comprehensive understanding on how MDSCs acquire their suppressi...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Lenneke A. M. Cornelissen, Kim C. M. Santegoets, Esther D. Kers-Rebel, Sandra A. J. F. H. Bossmann, Mark Ter Laan, Daniel Granado, Gosse J. Adema
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Subjects:
glioma
sialoglycans
Siglecs
myeloid cells
Online Access:https://www.mdpi.com/1999-4923/16/7/953

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https://www.mdpi.com/1999-4923/16/7/953

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