Association of the Serotonin and Kynurenine Pathways as Possible Therapeutic Targets to Modulate Pain in Patients with Fibromyalgia

Fibromyalgia (FM) is a disorder characterized by widespread chronic pain, significant depression, and various neural abnormalities. Recent research suggests a reciprocal exacerbation mechanism between chronic pain and depression. In patients with FM, dysregulation of tryptophan (Trp) metabolism has...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Alfonso Alfaro-Rodríguez, Samuel Reyes-Long, Ernesto Roldan-Valadez, Maykel González-Torres, Herlinda Bonilla-Jaime, Cindy Bandala, Alberto Avila-Luna, Antonio Bueno-Nava, Elizabeth Cabrera-Ruiz, Pedro Sanchez-Aparicio, Angélica González Maciel, Ana Lilia Dotor-Llerena, José Luis Cortes-Altamirano
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	tryptophan 5-HT1A 5-HT2 5-HT3 5-HTT quinolinic acid
Online Access:	https://www.mdpi.com/1424-8247/17/9/1205