Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages

Abstract Background Colony-stimulating factor 1 (CSF1) expression in the central nervous system (CNS) increases in response to a variety of stimuli, and CSF1 is overexpressed in many CNS diseases. In young adult mice, we previously showed that CSF1 overexpression in the CNS caused the proliferation...

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Bibliographic Details

Published in:	Journal of Neuroinflammation
Main Authors:	Ishani De, Vilena Maklakova, Suzanne Litscher, Michelle M. Boyd, Lucas C. Klemm, Ziyue Wang, Christina Kendziorski, Lara S. Collier
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Subjects:	CSF1 Microglia Astrogliosis Oligodendrogenesis
Online Access:	https://doi.org/10.1186/s12974-021-02212-0