Inhibiting influenza virus transmission using a broadly acting neuraminidase that targets host sialic acids in the upper respiratory tract

ABSTRACT The ongoing transmission of influenza A viruses (IAV) for the past century continues to be a burden to humans. IAV binds terminal sialic acids (SA) of sugar molecules present within the upper respiratory tract (URT) in order to successfully infect hosts. The two most common SA structures th...

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Bibliographic Details
Published in:mBio
Main Authors: Mila B. Ortigoza, Catherina L. Mobini, Hedy L. Rocha, Stacey Bartlett, Cynthia A. Loomis, Jeffrey N. Weiser
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Subjects:
influenza
transmission
sialic acid
neuraminidase
DAS181
Streptococcus pneumoniae
Online Access:https://journals.asm.org/doi/10.1128/mbio.02203-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02203-23

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