Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

Currently, no approved vaccines for Listeria monocytogenes are available. Here, the authors use immunopeptidomics to map bacterial peptides presented on infected cells and identify antigens that, as mRNA vaccine, provide protection in mice.

Bibliographic Details
Published in:Nature Communications
Main Authors: Rupert L. Mayer, Rein Verbeke, Caroline Asselman, Ilke Aernout, Adillah Gul, Denzel Eggermont, Katie Boucher, Fabien Thery, Teresa M. Maia, Hans Demol, Ralf Gabriels, Lennart Martens, Christophe Bécavin, Stefaan C. De Smedt, Bart Vandekerckhove, Ine Lentacker, Francis Impens
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Online Access:https://doi.org/10.1038/s41467-022-33721-y

Internet

https://doi.org/10.1038/s41467-022-33721-y

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