Inhibiting aberrant seizure-induced neurogenesis by temozolomide improves cognitive impairments associated with long-term amygdala kindling

In the adult dentate gyrus, new neurons are continuously generated and integrated into the existing circuitry where they play a crucial role in maintaining important functions related to learning and memory. Seizures not only robustly increase levels of hippocampal neurogenesis but can also induce a...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Travis J. Francis, Brady S. Reive, Hugo Lehmann, Neil M. Fournier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	adult neurogenesis pattern separation memory plasticity kindling seizure
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1626118/full