The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive–compulsive disorder: a comparative study with other treatment-resistant mental disorders

Abstract Background This study investigates the role of genetic variations in the 5-Hydroxytryptamine Receptor 2A (HTR2A) gene in subjects with treatment-resistant obsessive–compulsive disorder (TR-OCD), compared to individuals with other treatment-resistant mental disorders (TRMDs). The goal is to...

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Bibliographic Details
Published in:BMC Psychiatry
Main Authors: Antonio Del Casale, Giovanna Gentile, Jan Francesco Arena, Martina Nicole Modesti, Clarissa Zocchi, Serena Mancino, Ottavia De Luca, Gloria Angeletti, Stefano Ferracuti, Robert Preissner, Maurizio Pompili, Maurizio Simmaco, Marina Borro
Format: Article
Language:English
Published: BMC 2025-10-01
Subjects:
Obsessive–compulsive disorder
Depressive disorder
Treatment-resistant
Schizophrenia
Mental disorders
Online Access:https://doi.org/10.1186/s12888-025-07301-5

Internet

https://doi.org/10.1186/s12888-025-07301-5

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