Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer

Abstract Cancer immunotherapies, represented by immune checkpoint inhibitors (ICIs), have reshaped the treatment paradigm for both advanced non-small cell lung cancer and small cell lung cancer. Programmed death receptor-1/programmed death receptor ligand-1 (PD-1/PD-L1) and cytotoxic T lymphocyte-as...

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Bibliographic Details

Published in:	Journal of Hematology & Oncology
Main Authors:	Weishi Cheng, Kai Kang, Ailin Zhao, Yijun Wu
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Subjects:	Lung cancer Immune checkpoint inhibitor Bispecific antibody Combination therapy Biomarker
Online Access:	https://doi.org/10.1186/s13045-024-01581-2