PLGA-PVA-PEG Single Emulsion Method as a Candidate for Aminolevulinic Acid (5-ALA) Encapsulation: Laboratory Scaling Up and Stability Evaluation

One of the most widely used molecules used for photodynamic therapy (PDT) is 5-aminolevulinic acid (5-ALA), a precursor in the synthesis of tetrapyrroles such as chlorophyll and heme. The 5-ALA skin permeation is considerably reduced due to its hydrophilic characteristics, decreasing its local bioav...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Geisiane Rosa da Silva, Amanda Luizetto dos Santos, Andrey Coatrini Soares, Marinalva Cardoso dos Santos, Sandra Cruz dos Santos, Ştefan Ţălu, Vânia Rodrigues de Lima, Vanderlei Salvador Bagnato, Edgar Aparecido Sanches, Natalia Mayumi Inada
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	polymeric particles poly (lactic acid-co-glycolic acid) aminolevulinic acid polyethylene glycol
Online Access:	https://www.mdpi.com/1420-3049/27/18/6029