A Single-Step Method for Harvesting Influenza Viral Particles from MDCK Cell Culture Supernatant with High Yield and Effective Impurity Removal

Influenza vaccines, which are recommended by the World Health Organization (WHO), are the most effective preventive measure against influenza virus infection. Madin–Darby canine kidney (MDCK) cell culture is an emerging technology used to produce influenza vaccines. One challenge when purifying infl...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Sixu Liu, Jingqi Li, Qingtian Cheng, Kangyi Duan, Zhan Wang, Shuang Yan, Shuaishuai Tian, Hairui Wang, Shaobin Wu, Xinkui Lei, Yu Yang, Ningning Ma
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	influenza vaccine Madin–Darby canine kidney (MDCK) ion-exchange chromatography viral purification
Online Access:	https://www.mdpi.com/1999-4915/16/5/768