Regulation of iron metabolism and ferroptosis in cancer stem cells

The ability of cancer stem cells (CSCs) to self-renew, differentiate, and generate new tumors is a significant contributor to drug resistance, relapse, and metastasis. Therefore, the targeting of CSCs for treatment is particularly important. Recent studies have demonstrated that CSCs are more suscep...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Hailiang Wang, Zhongyan Zhang, Shiye Ruan, Qian Yan, Yubin Chen, Jinwei Cui, Xinjian Wang, Shanzhou Huang, Baohua Hou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Subjects:	CSCs ferroptosis iron metabolism lipid peroxidation GPX4-GSH FSP1-CoQ10
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1251561/full