Transparent tissue in solid state for solvent-free and antifade 3D imaging

Abstract Optical clearing with high-refractive-index (high-n) reagents is essential for 3D tissue imaging. However, the current liquid-based clearing condition and dye environment suffer from solvent evaporation and photobleaching, causing difficulties in maintaining the tissue optical and fluoresce...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Fu-Ting Hsiao, Hung-Jen Chien, Ya-Hsien Chou, Shih-Jung Peng, Mei-Hsin Chung, Tzu-Hui Huang, Li-Wen Lo, Chia-Ning Shen, Hsiu-Pi Chang, Chih-Yuan Lee, Chien-Chia Chen, Yung-Ming Jeng, Yu-Wen Tien, Shiue-Cheng Tang
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-06-01
Online Access:	https://doi.org/10.1038/s41467-023-39082-4