Palmitic acid activates NLRP3 inflammasome and induces placental inflammation during pregnancy in mice

Maternal obesity is one of the major risk factors for pregnancy complications and is associated with low-grade chronic systemic inflammation due to higher levels of pro-inflammatory cytokines such as interleukin (IL)-1β. Pregnant women with obesity have abnormal lipid profiles, characterized by high...

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Bibliographic Details
Published in:The Journal of Reproduction and Development
Main Authors: Michiya SANO, Sayaka SHIMAZAKI, Yasuaki KANEKO, Tadayoshi KARASAWA, Masafumi TAKAHASHI, Akihide OHKUCHI, Hironori TAKAHASHI, Akira KUROSAWA, Yasushi TORII, Hisataka IWATA, Takehito KUWAYAMA, Koumei SHIRASUNA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2020-02-01
Subjects:
inflammation
nlrp3 inflammasome
placenta
pregnancy
Online Access:https://www.jstage.jst.go.jp/article/jrd/66/3/66_2020-007/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jrd/66/3/66_2020-007/_pdf/-char/en

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