The immunomodulatory ballet of tumour‐derived extracellular vesicles and neutrophils orchestrating the dynamic CD73/PD‐L1 pathway in cancer

Abstract Head and neck squamous cell carcinoma (HNSCC) is a global cancer burden with a 5‐year overall survival rate of around 50%, stagnant for decades. A tumour‐induced immunosuppressive microenvironment contributes to HNSCC progression, with the adenosine (ADO) pathway and an upregulated expressi...

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Bibliographic Details

Published in:	Journal of Extracellular Vesicles
Main Authors:	Dominique S. Rubenich, Jordana L. Domagalski, Gabriela F. S. Gentil, Jonas Eichberger, Mathias Fiedler, Florian Weber, Marianne Federlin, Hendrik Poeck, Torsten E. Reichert, Tobias Ettl, Richard J. Bauer, Elizandra Braganhol, Daniela Schulz
Format:	Article
Language:	English
Published:	Wiley 2024-07-01
Subjects:	adenosine signalling biomarker cytoplasmatic PD‐L1 exosome head and neck squamous cell carcinoma immune checkpoint resistance
Online Access:	https://doi.org/10.1002/jev2.12480