Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance

Inverse vaccines that tolerogenically target antigens to antigen-presenting cells (APCs) offer promise in prevention of immunity to allergens and protein drugs and treatment of autoimmunity. We have previously shown that targeting hepatic APCs through intravenous injection of synthetically glycosyla...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Chitavi D. Maulloo, Shijie Cao, Elyse A. Watkins, Michal M. Raczy, Ani. S. Solanki, Mindy Nguyen, Joseph W. Reda, Ha-Na Shim, D. Scott Wilson, Melody A. Swartz, Jeffrey A. Hubbell
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Subjects:	lymph node subcutaneous tolerance glycopolymer regulatory T cell dendritic cell
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.714842/full