Liraglutide inhibits the proliferation of rat hepatic stellate cells under high glucose conditions by suppressing the ERK signaling pathway

Abstract Liver fibrosis is a common complication of diabetes. Due to the crucial role of HSCs in the pathogenesis of hepatic fibrosis, they are considered a key target in anti-fibrosis research. We designed this experiment to investigate the effects of liraglutide on the proliferation of rat hepatic...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Bingge Fan, Lingbing Meng, Xiao Zheng, Lei Bai, Yaping Du, Haiyan Ding, Yu Chen, Yuna Zhang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Subjects:	Hepatic stellate cells Liver fibrosis Liraglutide Hyperglycemia ERK signaling pathway
Online Access:	https://doi.org/10.1038/s41598-025-97872-w